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Oprah talks GLP-1 weight loss journey and how understanding obesity changed everything for her

January 2, 2026
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Oprah Winrey is on the duvet of Individuals journal AGAIN!

For many years the enduring speak present host and leisure mogul has lived out her relationship with weight in public; from headline-making weight loss plan moments to deeply private reckonings round disgrace, self-discipline and self-blame. Now, she’s naming what she says lastly modified the dialog for her: understanding weight problems as a illness.

In a brand new interview with Individuals, Oprah shared that the largest breakthrough got here when she stopped seeing overeating as the basis drawback and as an alternative acknowledged that weight problems itself was driving her habits.  Winfrey instructed the journal that understanding she suffers from weight problems and wishes assist to combat it, led to her determination two and a half years in the past to begin taking GLP-1 weight-loss medicine.

“I assumed it was about self-discipline and willpower. However I finished blaming myself,” says Winfrey. “I really feel extra alive and extra vibrant than I’ve ever been.”

Winfrey says the epiphany got here when she hosted a particular on weight problems in 2023 with consultants within the area.

“I prevented the phrase ‘weight problems.’ It connoted ‘uncontrolled,’ ” she says. “However I got here to know that overeating doesn’t trigger weight problems. Weight problems causes overeating. And that’s essentially the most mind-blowing, releasing factor I’ve skilled as an grownup.”

Whereas Oprah shied away from sharing her present weight, she did reveal that earlier than GLP-1’s her weight appeared to all the time creep again as much as 211 kilos.

“I wished to be a type of individuals who might be at peace with myself being obese,” she says. “However the whole lot in my life, within the tradition, in society, in my mind, was telling me the alternative: ‘You’ve failed as a result of you haven’t conquered this factor.’ ” And, she says, “I used to be not wholesome at 211 lbs. Lots of people inform me they are often obese and wholesome. I used to be not. I used to be pre-diabetic, and my ldl cholesterol numbers have been excessive.”

Winfrey says she’s solely skilled minimal negative effects whereas utilizing GLP-1’s, including that consuming sufficient water and taking magnesium have helped her modify. She additionally added that one surprising facet impact of the medicine has been her newfound indifference to alcohol.

“I used to be an enormous fan of tequila. I actually had 17 photographs one evening,” she says. “I haven’t had a drink in years. The truth that I not actually have a need for it’s fairly wonderful.”

She additionally says her relationships have improved, and shared that the adjustments have been so impactful for her that she’s sought to assist others as properly, paying out of pocket for GLP-1 medicine for numerous acquaintances who couldn’t afford them.

“In case you have weight problems in your gene pool, I would like individuals to understand it’s not your fault,” Winfrey instructed Individuals. “I would like individuals to cease blaming your self for genes and an surroundings you possibly can’t management. I would like individuals to have the data, no matter you select to do with it, whether or not you get the medicines, or whether or not you need to hold weight-reduction plan.”

Whereas Winfrey continues to eat wholesome and works out six days per week (two hours of climbing, cardio or resistance coaching) she believes her use of GLP-1s shall be “a lifetime factor.”

A month shy of 72, Oprah says she feels stronger, freer and extra at peace than she has in years.

Winfrey shares extra about her journey in a brand new e-book with weight problems professional Dr. Ania M. Jastreboff, Sufficient: Your Well being, Your Weight and What It’s Prefer to Be Free, out Jan. 13.





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